Drug Development Essay - 1537 Words

Drug development This entire section on drug development highlights concerns which are very particular to the industry. They therefore lead to the implementation of CSR activities which are also very industry specific, although aspects such as animal testing and ethics in research can be shared by other industries such as the cosmetics industry, or the medical device sector for instance. Need for RD and innovation Today, the need for RD and innovation is great, maybe greater than ever. In the developed world, access to medicines is becoming a society’s demand and an ever increasing expectation from patients. Yet, in spite of the significant amount of medicines that have been developed over the decades, there are still many diseases†¦show more content†¦However, any new drug, any new medical advance comes from years of research and development by pharmaceutical companies. The development of a new drug is a progressive filtering process (Taylor, 2005). Typically, of a starting pool of 10,000 molecules screened as potential new drugs, only a dozen will make it to preclinical trials. Eventually, after clinical trials on animals then humans, only one or two of the original 10,000 molecules will make it to the ultimate marketing authorization stage and commercialization to patients (Les Entreprises du Mà ©dicament, 2008). Overall, the process will take 7 to 12 years to complete, with a cost of development reported to be US$800 million for each drug (Dickson Gagnon, 2004). Understandably, with such lengthy processes and need for extensive investment, and given the fact that developments of drugs are the endeavors of private entities, only companies with substantial profits can re-inject their benefits into research and development. This not only limits the number of companies that can perform RD but also potentially affects the span of diseases that can be studied and addressed. Orphan drugs There are a number of issues at stake when it comes to Orphan drugs, drugs which are aimed at treating very rare diseases and defined by WHO as affecting less than 1000Show MoreRelatedThe Development Of Drug Addiction Essay814 Words   |  4 PagesUndoubtedly, a huge role in the women abuses plays by the biological characteristics of the development of drug addiction. The most important are features of a constitution and hormonal difference, which significantly affect the pharmacokinetics of drugs (NIAA, 2015). In general, women have a lower activity of hepatic enzymes related to drug metabolism. Resulting from the body weight and a higher ratio of fat tissue in relation to the muscle, there is a higher concentration of surfactant in the bloodRead MoreDrug Discovery And Development Of New Medicine1417 Words   |  6 PagesDescribe and discuss recent developments in drug discovery. 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