Drug Development Essay - 1537 Words

Drug development This entire section on drug development highlights concerns which are very particular to the industry. They therefore lead to the implementation of CSR activities which are also very industry specific, although aspects such as animal testing and ethics in research can be shared by other industries such as the cosmetics industry, or the medical device sector for instance. Need for RD and innovation Today, the need for RD and innovation is great, maybe greater than ever. In the developed world, access to medicines is becoming a society’s demand and an ever increasing expectation from patients. Yet, in spite of the significant amount of medicines that have been developed over the decades, there are still many diseases†¦show more content†¦However, any new drug, any new medical advance comes from years of research and development by pharmaceutical companies. The development of a new drug is a progressive filtering process (Taylor, 2005). Typically, of a starting pool of 10,000 molecules screened as potential new drugs, only a dozen will make it to preclinical trials. Eventually, after clinical trials on animals then humans, only one or two of the original 10,000 molecules will make it to the ultimate marketing authorization stage and commercialization to patients (Les Entreprises du Mà ©dicament, 2008). Overall, the process will take 7 to 12 years to complete, with a cost of development reported to be US$800 million for each drug (Dickson Gagnon, 2004). Understandably, with such lengthy processes and need for extensive investment, and given the fact that developments of drugs are the endeavors of private entities, only companies with substantial profits can re-inject their benefits into research and development. This not only limits the number of companies that can perform RD but also potentially affects the span of diseases that can be studied and addressed. Orphan drugs There are a number of issues at stake when it comes to Orphan drugs, drugs which are aimed at treating very rare diseases and defined by WHO as affecting less than 1000Show MoreRelatedThe Development Of Drug Addiction Essay814 Words   |  4 PagesUndoubtedly, a huge role in the women abuses plays by the biological characteristics of the development of drug addiction. The most important are features of a constitution and hormonal difference, which significantly affect the pharmacokinetics of drugs (NIAA, 2015). In general, women have a lower activity of hepatic enzymes related to drug metabolism. Resulting from the body weight and a higher ratio of fat tissue in relation to the muscle, there is a higher concentration of surfactant in the bloodRead MoreDrug Discovery And Development Of New Medicine1417 Words   |  6 PagesDescribe and discuss recent developments in drug discovery. As our society is evolving so is diseases many drugs that were previously effective to cure certain diseases are simply not as effective any more or on the other hand there isn’t sufficient medicine to battle the current new health problems that are arising with our evolving society for example obesity and a range of cardiovascular diseases. In addition many of the medicine available today either only treats the symptom or cures the diseaseRead MoreChildhood Development And Parental Drug Use Essay1872 Words   |  8 Pagesinfluence over their children s development and although kids come with their own temperaments, it is ultimately the parents job to provide an interface with the world to help the child prepare for complete independence in a rapidly changing world. Parents play the lead supporting role in their children s learning and development and influence a child s well-being. But what happens when a child’s parents are not actively involved in their lives and a buse drugs? 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These medications were efficacious, but had issues with systemic toxicities due to their non-selectivity of diseased cells or disease causing proteinsRead MoreDrugs And Drug Development Journey1804 Words   |  8 Pagesto antipsychotics The drug development journey leading to olanzapine (Zyprexa) reaching the market did not always follow the steps of rational drug design. Inspired by the first antipsychotic drugs, it took a while from the first discovery of antipsychotic drugs until Zyprexa was developed. The first antipsychotics were come across largely by chance. They were not specifically tailored to a relevant biological effector as rational drug design promotes. Even now as most drugs, Zyprexa is not quiteRead MoreDrug Development: Preclinical Development and Testing1548 Words   |  6 PagesWhen a drug is developed its safety and efficacy has to be established to qualify for a licence to market it in Ireland – Irish Medicines Board or in the USA from the Food Drug Administration. The drug undergoes a series of tests to prove its medicinal ability is sufficient for the medicines market. Preclinical Development Preclinical testing performed by graduate researchers (Ph.D level), evaluate the medicines safety and efficacy before the medicine can be tested on humans. The medicine isRead MoreDevelopment Of Drug Design : A New Anticancer Drug1102 Words   |  5 PagesFAMOUS SCIENTIST REVIEW Development of Drug Design Scientists aim to produce a new anticancer drug which will meet all requirements by exploring and understanding the structure and reactivity of the molecule. It is specifically focused on transition metal-based anticancer drug. Transition metals have unique properties and reactivity. They have different oxidation state which able them to interact with molecules of different negative charges. The metals are co-ordinated by different ligands whichRead MoreThe Drug Development And Approval Process1179 Words   |  5 PagesKrishna (2008) article, the drug development and approval process is an extensive and costly endeavor. The goal of experimental medicine is to increase the efficiency of drug development by providing a better understanding of the drug’s mechanism(s) of action, dose response, efficacy, and safety, allowing the process to be accelerated for the most promising and efficacious candidates (Krishna, Herman, Wagner, 2008). Preclinical testing begins with identifying the ideal drug target. The target should

The Obesity Epidemic Hitting America and How to Stop It

Attention: I will be the first to admit, I was not a lean child by any means. I was involved in many sports, but regardless of how much physical exercise I was involved in I was still heavy. I was always tired and found myself not being able to compete to level in which I wanted to be at. My weight was not only holding me back, but making me sick. While diets like South Beach, helped me to eventually start becoming more healthy, they were not comprehensive enough and still had elements that would not allow me to preform my best or continue to feel sick. These are common problems not only amongst youth, but weight related issues are now affecting people of all ages, races, and socioeconomic statuses. Today I will be discussing the issue of America becoming increasingly overweight and obese and will present a a possible way of remedying the impending epidemic. Problem/ Need: Today in America people are not eating well. People are becoming increasingly sick due to an increase in improper diets. Obesity and weight related disease are at an all time high and continue to plague the United States. According to the Food Research and Action Center, 69% of adults are overweight or obese; 35% are obese. 32% of children and adolescents are overweight or obese; 17% are obese. 31% of low-income preschoolers are overweight or obese. Weight related diseases are are no longer just a health concern, but an economic problem. The Center for Disease Control and Prevention has stated thatShow MoreRelatedObesity Is An Epidemic Across The United States1592 Words   |  7 PagesObesity has become an epidemic across the United States. Americans have continued to gain weight, increasing the amount of people that are considered obese by millions every few years. More and more experts have come to a consensus: weight needs to be addressed and changed in America. Many experts, however, have not found a way to completely solve this problem at large. In the article, â€Å"Rethinking Weight†, senior writer Amanda Spake directs attention to the barriers our society has built for obesityRead MoreObesity Epidemic Around The World2602 Words   |  11 PagesObesity Epidemic around the World The Walt Disney production â€Å"Wall-E† is a portrayed image of what our world could soon become. If you aren’t familiar with what the film is about, it is about obese humans relying on technology to do everything and anything for them. They weren’t concerned with their health at all, ordering jumbo soda and super-sized meals of fast food, for every meal. As Wall-E broads the ship and knocks some humans out of their delusional life style, they begin to realize somethingRead MorePoverty Obesity2526 Words   |  11 PagesConnection between Poverty and Obesity English 135 DeVry University Farm subsidy payments are over $10 billion and are authorized to make payments to people â€Å"who aren’t even farmers anymore† (Morgan, Gaul, Cohen, 2006, para. 3). This has been going on, in some cases, over 10 years (para. 6). As long as you owned the farmland, you don’t even have to be growing anything and you would continue to receive a subsidy check (para. 3). Bottom line is all these billions of dollars in governmentRead MoreChildhood Obesity: a Growing Epidemic Essay2304 Words   |  10 PagesChildhood Obesity: A Growing Epidemic Matt Vogel University of South Dakota Introduction: Would you like to super-size this meal for an extra $.39? That is a question far too many Americans hear everyday. People in this country are getting fatter and fatter. In a study conducted by the independent Institute of Medicine (IOM), the prevalence of obese children age 6 to 11 is three times as high as 30 years ago, (Arnst and Kiley, 2004). Additionally, 31% of the total U.S. population is classifiedRead MoreWhat Was the American Diet Like 50 Years Ago8269 Words   |  34 Pages xxv) And in a less disposable age there was always plenty of darning and mending to do by the fire. ) Prima editor Maire Fahey said the magazine decided to study the contrasting lifestyles following an earlier survey, which revealed how todays women were neglecting their health. xxvi) It is telling that modern technology has made us two-thirds less active than we were. It goes to show the importance of exercise in the battle to maintain a healthy balance. ) ExerciseRead MoreBusiness Ethics6288 Words   |  26 Pageslifestyle s drastic effects on Spurlock s physical and psychological well-being, and explores the fast food industry s corporate influence, including how it encourages poor nutrition for its own profit. The reason for Spurlock s investigation was the increasing spread of obesity throughout U.S. society, which the Surgeon General has declared epidemic, and the corresponding lawsuit brought against McDonald s on behalf of two overweight girls, who, it was alleged, became obese as a result of eatingRead MoreEthical and Social Issues in Information Systems20165 Words   |  81 Pagesinformation society and specific principles for conduct that can be used to guide ethical decisions. 3. Evaluate the impact of contemporary information systems and the Internet on the protection of individual privacy and intellectual property. 4. Assess how information systems have affected everyday life. CHAPTER OUTLINE 4.1 UNDERSTANDING ETHICAL AND SOCIAL ISSUES RELATED TO SYSTEMS A Model for Thinking About Ethical, Social, and Political Issues Five Moral Dimensions of the Information Age Key TechnologyRead MoreExploring Corporate Strategy - Case164366 Words   |  658 Pages22/10/2007 11:54 Page 599 Guide to using the case studies The main text of this book includes 87 short illustrations and 15 case examples which have been chosen to enlarge speciï ¬ c issues in the text and/or provide practical examples of how business and public sector organisations are managing strategic issues. The case studies which follow allow the reader to extend this linking of theory and practice further by analysing the strategic issues of speciï ¬ c organisations in much greater depthRead MoreStephen P. Robbins Timothy A. Judge (2011) Organizational Behaviour 15th Edition New Jersey: Prentice Hall393164 Words   |  1573 Pagesreproduced, with permission, in this textbook appear on the appropriate page within text. Copyright  © 2013, 2011, 2009, 2007, 2005 by Pearson Education, Inc., publishing as Prentice Hall. All rights reserved. Manufactured in the United States of America. This publication is protected by Copyright, and permission should be obtained from the publisher prior to any prohibited reproduction, storage in a retrieval system, or transmission in any form or by any means, electronic, mechanical, photocopying

TOEFL Grammar Quiz Exam Prep

Word Collision Christopher Columbus and The Taino Natives

The swift sandy beaches of the Caribbean were once desolate and unknown rule by the natural habitat of Taino natives whose sole existence revolved around primitive nature. These Virgin Islands would be a critical and strategic discovery for the strengthening Spanish empire during the 15th century under the rule of Ferdinand of Aragon and Isabel of Castile . On October 1492, a man by the name of Christopher Columbus would take the power of the Spanish crown to excellency and great dominion over the new world. The lives of both the natives and the Spaniards would be revolutionized and two completely different worlds would collide for the first time. The discovery of the New World was masked by preconceptions, ancient interpretations of†¦show more content†¦Consequently, Columbus states that the Indians have a closer relationship to the lord based on their lifestyle, selflessness, and kindness to strangers. Moreover, in this letter he also ascertains a degree of innocence in th e Indians while drawing a distinction amongst the Europeans advantageous actions in the exchanges for broken objects for pieces of valuable gold. Throughout the letter, Columbus describes his prohibition in the colonists to trade with the Indians since he deemed it unfair to trade something worthless to the Spaniards for gold that would grant them and the crown more wealth. Columbus’ ulterior motives are dominated by the socio-cultural and religious teachings of the Catholic Church. Ferdinand of Aragon and Isabel of Castile, both proclaimed as God given kings, wanted full centralization of their established autocratic governance. The goal of expansion into the western world would be to propagate the dominion of the Catholic Church and the power of the Spanish empire to lands unknown to humanity at the time before the Portuguese and other imminent powers. As a discoverer, Columbus was shaped by the crusading environment he grew up in as well as the desire of annexation of l and. The main paradox between the first encounter is presented in the belief system of the Indians whom have faith in nature as their ruling God, such beliefs are mirrored to those of the ancient Greeks and in the

Stalin- an Evil Dictator Free Essays

Stalin: Man or Monster 1. Source A shows Stalin as a man intent on destroying the prosperity of Russia and destroying its people. In contrast, source B is showing the opposite. We will write a custom essay sample on Stalin- an Evil Dictator? or any similar topic only for you Order Now Source A shows Stalin proudly presenting ‘the USSR’s pyramids’ made of the skulls of the people. He has a big grin on his face. Meanwhile, source B shows Stalin talking with the workers at a new power station. He is presented as wanting to connect with this people and caring by how he is taking with what is regarded as the lower-class when he is regarded as the most important person in Russia. Source C presents Stalin as the spirit of Russia and the symbol of power of Russia by how he is very large in comparison to everything around him which emphasises his power and strength as does the huge army around him. In comparison, source A shows Stalin as the symbol of the destruction of Russia because of the large quantities of human skulls with Stalin presenting them with a smile show how he is planning to destroy Russia which is the exact antithesis of source C. Source B and source C both show Stalin as pro the development of Russia. Source B shows Stalin in front of a brand new power station which shows that he is industrious and looking out for the people of Russia by improving their lives. Source C also shows Stalin leading the Russians to victory in the war and he is the subject of the poster which directly links him to all Russian success and power. Both of these sources put Stalin in a positive light. 2. Source D presents Stalin as a caring and brave man who is the only man in a position of power who cares for others because he talks about how he saved a man from drowning when others did not care. Although Stalin wrote it and therefore it is probably not factual but just propaganda, it still is useful as it says a lot about him. If this was made public then it can be argued that Source D was used as propaganda in order to win the hearts of the people after the war. It was written in 1945 so just after the war and the last sentence indicates that it was possibly used to get people on his side. Stalin says that ‘it seemed to me that the lack of concern our leaders show towards the people is the same as I met in far-off Asia’. The fact that he uses the word ‘our’ in relation to the leaders indicates that he was distancing the himself from the mistakes made and trying to say that he is just like anyone else. Also the reference to ‘Asia’ indicates he is trying be one of the soldiers as he had fought for Russia and that he is trying to sympathise with them after many millions of Russians died. However this last sentence could also be Stalin apologising for his mistakes with The Great Purges when 18 million people were sent to labour camps called Gulags of which 10 million died. This seriously weakened the USSR as many able people were taken away. Also he is trying to claim that he is very caring by using the story about a comrade being left behind in the floods. He says that ‘when asked where he was, they (other comrades) replied with no interest that he remained at the river’. This shows Stalin attempting to present himself as the only caring person in a position of power. This gives further evidence that Stalin believed he was a very caring person and good leader which can be argued as very arrogant as he never really showed this to his people when he was in power. In conclusion, Source D, although it is unlikely that it is true, says a lot of useful things about Stalin and what he was believed. It shows him as very arrogant as he may be trying to distance himself from the mistakes of his regime and also because he thinks he is caring when from historical evidence he was not. Also, if it was published which seems almost certain, it shows that he was a determined man as he tried to make sure his position was safe by using a propaganda story which is probably not true. 3. Both Source E and Source F are written by people with very different views of Stalin. In Source E’s information it says it was published in ‘Pravda, the newspaper of the Communist Party’ whilst in Source F it says it was written by a man called Bukharin who ‘was a victim of Stalin’s purges’. This means that both are likely to subjective as the writer of Source F is anti-Stalin whilst Source E is pro-Stalin therefore not very reliable . Having said this, Bukharin’s view of Stalin is more likely to be correct as he was taken advantage of when Stalin was a candidate for Lenin’s position. Stalin took Bukharin’s side in the debate on the NEP in order to get rid of his main threat-Trotsky. Once he achieved this he used Trotsky’s argument to oppose Bukharin. This there for means that Bukharin has seen, firsthand, what Stalin’s actual character is. Source E presents Stalin as a very caring leader and an ‘inspired leader’. However, Source F presents him as the antithesis of this and a ‘devil’. Again based on historical fact, Source F is more likely to be accurate as history shows that Stalin was an evil man. For example the purges when 10 million people died. Source F is also very accurate in its description of Stalin’s feelings to others who are better than him. It says that ‘if someone speaks better than he does†¦ Stalin will not let him live’. This is very accurate as Kirov, who got more applause than Stalin at the Seventeenth Party Congress, was murdered. There was a lot of talk of removing Stalin as leader, and Kirov seemed to be emerging as a popular alternative. Stalin is believed to have him murdered and also he sent many other leading communists to labour camps because he felt they were a threat. However Source F does have its limitations because it does not cover all aspects of Stalin’s personality because he was actually a very successful leader. And this is where source E has reliable information even if it is slightly exaggerated. Stalin got the Russian industry at its peak and his Five-year Plans, although they had disadvantages, were very successful. Pig iron production in 1927 was 3. 3 million tons but after the second Five-Year Plan in 1937 in was 14. 5 million tons. In the same time coal production went from 35. 4 million tons to 128 million tons. This shows that Stalin was actually very successful and this is reflected in some people’s opinion he was regarded as the greatest Russian leader to date. Source E agrees with this opinion as it says ‘generations to come will regard us as the happiest of people because we lived in the same century as Stalin’. This is actually very reliable as many people did believe he was a great leader and in terms of statistics he successfully industrialised Russia. Source E also talks about his ‘strength’ as a leader. This is also very accurate information as his army were the ones who drove the Germans back into Berlin and finished off the war. In conclusion, based on reliability Source F is the more reliable as it shows the negative side of Stalin which is contextually correct as he shows it in his actions towards Kirov and other leading communists who some had said should be leader instead of him. Having said this, Source F portrays Stalin as only pure evil when he did do some positive things. This is where Source E has some reliable information as it talks about Stalin’s strengths even if the source is a bit melodramatic about it. 4. A leader of a country can be a strong and great leader and a monstrous tyrant. Stalin was a man who people had different views on and many felt feel into this category. Although he modernised Russian agriculture and successfully industrialised Russia he was also responsible for the death of millions of innocent Russians. Source B presents all that was good about Stalin in his rule. Its shows Stalin in front of a new power station talking with his happy workers. It presents him as industrious and caring for his workers. This is supported by historical evidence. He had many new flats buildings built for the working-class and from 1927-1937 electricity production went from 5. 05 thousand million kilowatt hours to 36. 2 thousand million kilowatt hours. This shows how he improved life in Russia. Having said this, historian SJ Lee said ‘there is evidence that he [Stalin] exaggerated Russia’s industrial deficiency in 1929’ and that the foundation of industrialisation were already there making his job easy. This could be factually correct as the Tsar had started industrialising Russia way back in 1905. Despite this Source B still presents Stalin as a very good leader and a caring man. Source C presents Stalin as the most important man in Russia and the leader of the Russian army as in the picture he is bigger than the whole army. This presents in a positive manner a not a monstrous tyrant but more of a militaristic leader. This is backed by the fact that when he was in power Russian won World War 2 for the allies with the final push into Berlin. The writing in the source is translated as ‘using the spirit of Stalin our army and country are faithful and strong’. This is very true as in the time of Stalin Russia were the biggest threat to the USA as the biggest power in the world. He also did become regarded as the symbol of Russian might by everyone. In 1925 the city of Volgograd was renamed Stalingrad to recognise Stalin’s role in its defence from the Whites in 1918-20. This source shows Stalin as a very powerful leader and the spirit of Russia and not a monstrous tyrant at all. Source E emphatically praises Stalin as ‘inspired’ and tells everyone that they were ‘the happiest of people because we lived in the same century as Stalin’. And this is not entirely rubbish. Although at points in his rule the Russian people were miserably as 18 million of them were in Gulags, for a lot of his rule only good things happened to Russia. Industry improved rapidly and Russia won a war in his time. Many regarded him as the greatest leader in Russia’s history. However it was written by a writer in the congress of soviets and therefore was closely linked to Stalin. This makes it likely that he wrote this speech in order to appease Stalin and get in his good books. This source portrays Stalin as a great man and leader who was the best leader Russia had had. It shows him as the antithesis of a monstrous tyrant. Source H talks only about the side of Stalin which was actually true: that he was a good leader and had an ‘iron will’. Of this there is no doubt as he did what he wanted. He was indeed a good leader and was always clear with his decisions as the source. However this source is certainly going to be pro-Stalin as it was written in Russia in his rule and was his biography. This shows that it therefore would not talk about the other side of his personality which was arguably a monstrous tyrant. However despite this, what source H is saying is not just lies and is based on truth. This source indicates that he is not a monstrous tyrant but a respected leader which is not wrong. Source D dissociates Stalin from the mistakes of the leaders in the war and also dissociates him from the great purges when millions of Russians died. It is also presenting him as one of the people by how it says ‘our leaders’. The use of the possessive adjective ‘our’ shows him not only distancing himself from the past mistakes in his rule but trying to connect with the people. Source D also shows him as a caring man as he looked out for his one missing comrade in the story. This source is not however really backed by historical evidence as he was not one for caring for individuals and in fact he was the one who on his own started the Great Purges and sent many to gulags. Also the fact that it was written by Stalin himself indicates that the story is almost certainly made up and only propaganda. However, taking the source for what it is, it shows that Stalin was a very caring man who was one the people. In actual fact he was quite the opposite. Source I is probably the fairest judgement of Stalin and his time in power. It separates Stalin’s great ability as a leader from his evil personality. The fact that it was published in Britain and in 1983 means that it is unlikely to have any reason to be pro or anti-Stalin. This source describes him as a ‘very skilled, indeed gifted politician’. This is a true statement as he very cleverly manipulated people and Trotsky’s underestimation of him to become leader over Trotsky. This shows a very good political mind and intelligence to outwit even the best politicians. Source I then concludes that Stalin was a not a good man and that ‘he had a dark and evil side to his nature’. This is also very true as he had many sent to Gulags in order that he would look powerful. Of the 18 million people sent to Gulags 10 million died. And he never officially conceded that he made a mistake and never said he regretted it. This shows a very sinister side to him which Source I correctly points out. Also he was evil in the way that he got rid of many artists and virtually destroyed the right to express freewill in Russia. This can only be the work of someone who is soulless and evil. In conclusion, although this source looks at Stalin’s positives, it still portrays him as a monstrous tyrant. Source A dwells on the negatives of Stalin’s rule. The ‘pyramids’ of skulls is a reference to the Great Purges when 18 million Russians were sent to Gulags of which 10 million died. This source also seems to show that Stalin does not care and in fact is very proud of his work. This is actually not complete rubbish as Stalin never did publicly apologise or even say he regretted it. However, the fact it was published in Paris indicates that it may be a bit anti-communism as France was a country which did not embrace communism at all. Although we do not know when in the 1930s it was published- before, after or during the Purges- it is a very accurate source as many died due to Stalin’s policies. This source indicates that Stalin was a monstrous Tyrant. Source J literally describes Stalin as a ‘monstrous tyrant’. However, as oppose to saying he was a good politician but also a malevolent human being, it suggests that was corrupted by ‘absolute power’ which ‘turned a ruthless politician into a monstrous tyrant’. This gives another idea about Stalin’s personality. There was no doubt that he was a ruthless politician. For example, after using Bukharin’s argument to defeat Trotsky, he then turned it round on Bukharin and used that argument to disgrace him. However after Stalin’s decisions do not really show politics in them but more him being paranoid about his position and therefore doing acts of hostility. For instance, his decision to start ‘purging’ Russia of all people he thought were a threat to the state ( or a threat to his position†¦ ) did not show clever politics but more panic leading to monstrous acts. This source present Stalin as a man who may of been great politician in the past but then this ability of his turned into shear malicious tyranny. Source F concentrates on the dark side of Stalin’s personality. It says that ‘if someone speaks better than he does†¦ Stalin will not let him live’. This is debatably a very accurate description of Stalin as he was rumoured to have had Kirov, a communist who became very popular and some people thought should replace Stalin at the time, was murdered and many believe that Stalin was behind the murder. Stalin also sent many loyal Bolsheviks to Gulags in the infamous ‘show trials’ for being traitors of the state. Although these people confessed, Stalin most probably forced them to confess by threatening them with death and the death of their families. He did this because he was scared they would take away his power. Having said this, this source is likely to be subjective as Bukharin, the writer of the source, was disgraced by Stalin in 1929. Also it is a very one-sided source as it says that Stalin was pure evil when he did do good things for Russia. To conclude, although it is slightly opinionated, Source F gives a fairly accurate account of what was wrong with Stalin and displaces him as malicious and as the devil. Source G points the finger at Stalin by accusing him of using ‘terror’ to defend communism. However, this source is almost certainly prejudiced against Stalin as Khrushchev, who said source G and became leader after Stalin, would have been trying to distance himself from the worst parts of Stalin’s rule by condemning him. Although, Source G does have some correct ideas as it says that Stalin was a ‘distrustful man’. This is an accurate description of Stalin as he had many sent to Gulags because he thought they were plotting against him. He also acted very suspiciously at the Potsdam Conference in August 1945 when in February that year at the Yalta conference he had been very united with the other allies. At Potsdam Conference he disagreed with the other allies about what to do with Germany, about reparations and over soviet policy in Eastern Europe, where Russian troops dominated. Truman, the USA president at the time, became suspicious of Stalin and his intentions, as did Stalin. This distrusted lead to the Iron curtain and the cold war. To conclude, Although Khrushchev was not likely to have praised Stalin in this situation, Source G is a very accurate description of Stalin and portrays him as untrustworthy character and malicious tyrant. In conclusion, the sources do not give a conclusive idea to whether he is a monstrous tyrant or not because five of them are anti-Stalin and 5 pro-Stalin. However, based on the fact that many of the Pro-Stalin Sources are either written by Stalin or as propaganda, the ources show that he more of monstrous tyrant. Also the sources which focus on his industrious nature and his successes in improving industry do not take into account how many people died in this process and that Russia’s industry had been improving a lot for the twenty years before Stalin came to power. In essence his job on that was made easy and some historians argue that this process would have happened just as successfully with any leader. A leader can be great at being a politician and be industrious yet still be a monstrous. My personal opinion is just that, that he was a great leader and politician however a very evil man and therefore a monstrous tyrant. Source I sums up Stalin as a person. It says Stalin is ‘very skilled, indeed gifted politician and one of the greatest political figures of the twentieth century’ however it also says ‘he had a dark and evil side to his nature’. This summarises perfectly Stalin’s life: he was a great leader of a country however he was still a very evil man and a monstrous tyrant. How to cite Stalin- an Evil Dictator?, Essay examples

Museum of Fine Art Kunsthistorisches Museum Essay Example For Students

Museum of Fine Art: Kunsthistorisches Museum Essay The Museum of Fine Arts building is located at Wiener Reintegrates, at the opposite side of the Undernourishment Museum. The interior of the Constructionists Museum, signed by Karl non Hastener, is spectacular, with large marble columns, monumental staircases and statues. The huge collection of the museum was amassed by the Hapsburg monarchs, and hence is a reflection of their personal tastes. The Gemlike, the collection of paintings, is one of the largest in the world and spans an era from the 15th to the 18th century. Especially well represented are Flemish artists. Dutch, Italian (mainly Venetian) and Spanish artists are also well represented. The museum also has an excellent collection Of German paintings from artists such as Albrecht Udder and Hans Holing the Younger. Theres more than just paintings in the Constructionists Museum though. On the ground floor are Roman and Greek antiquities; here youll find a large number of statues and busts from Roman emperors as well as Greek vases and statues. One of the museums most important objects, the Ceiling Salt Cellar sculpture by Benevolent Ceiling, was stolen on May 11, 2003 and recovered on January 21, 2006, in a box buried in a forest near the town of Sweetly, Austria, It had been the biggest art theft in Austrian history One tooth best times to visit the Constructionists Museum is Thursday, when you can enjoy a sumptuous gourmet dinner (?39) in the cupola rotunda.. This museum is the museum for you if you like to enjoy different types of art over different areas of time, I love Egyptian art and this museum does a thorough and beautiful exhibit on Egyptian pieces of art. If you do not speak German I cannot recommend the audiogram enough at G each me and my partner shared ending up getting a lot more out of the exhibits as all of the little signs with information are in German. The audiogram Vass easy to use, descriptive and interesting.

Caribbean Journal free essay sample

Caribbean Journal He stands outside the fencing looking in. Inside, sunbathers relishing their flesh some white, some black, and some of other skins diving and swimming, feign not to notice him, fingers of doubt spread wide, gripping holes of mesh. Some people on the grass are picnicking. His pants are torn; he does not have a shirt; his face, a mask of sun-flaked grease and dirt, too young to understand his day’s events, dreams mountain-slide of magic dollars and cents to cancel knowledge of the stomach’s pain; eyes learning what will later reach his brain. In time they’ll be afraid to hear his curse at god’s unholy Sunday-school arrangement, put him inside wire-mesh or worse, and sunbathe in the same sun on his hearse or perish if his bullet gets them first. [Cecil Gray] 1. In a single word or short phrase, state what you consider to be the most dominant subject or idea that the poem communicates. We will write a custom essay sample on Caribbean Journal or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page (1 mark) Classism, rich versus the poor. 2. In a single sentence, state the theme or statement that the poem makes (implies) about the subject you selected. (2 marks) Classism places the poor at a disadvantage as their future is often dictated based on stereotypical views. 3. Identify and list three effective techniques or devices that help to convey this statement. For each device you identified, write a brief statement (one sentence) explaining its effectiveness (what it contributes to the poem, its function). (6 marks) The speaker made use of metaphors, visual imageries and rhyme to convey the subject of classism. The metaphor such as ‘his face, a mask of sun-flaked grease and dirt’ was strictly implied by the speaker to describe how the young poor boy looked, in a demeaning way- he was not even compared to, his features were directly grease and dirt, hence the stereotyping, classism. The visual imageries such as, â€Å"Inside, sunbathers relishing their flesh†, provided a vivid description of the social classes and also explained profoundly the future the speaker predicts for the young, poor boy. The rhyme allowed for better understanding of the poem, as it allows for the poem to be read a certain way emphasizing on certain words and providing a natural flow to the poem. 4. Taking into consideration your responses thus far, formulate a working thesis you could use to guide your analysis of this poem. (5 marks) The speaker presents two conflicting social classes, the rich versus the poor. With the use of rhyme, metaphors and visual imageries, the speaker effectively portrayed how the poorer class youths are negatively stereotyped. 5. Using between 80 and 100 words, present the introductory paragraph (which of course must include your thesis) of the critical analysis essay you would write. (6 marks) Classism has been an ongoing social problem in the Caribbean. Too often the poorer people are being oppressed, marginalised and stereotyped, due to their limited and inadequate resources. As a result of this, society has formulated negative images and conceptualizes ideas about the poor that has become fixed and widely accepted. â€Å"Caribbean Journal† by Cecil Gray, is one such literary presentation that justifies the fact that the poor is negatively stereotyped in society. The poem portrays the rich, enjoying life at its best, picnicking and having fun, and poor, young, dirty and hungry boy observing them, daydreaming about the life and world of the rich. The speaker then predicts that the boy will become frustrated, hence he will become a blasphemer, a criminal, go to prison, or even worst-die, a future determined by the stereotypes of society. The speaker presents two conflicting social classes, the rich versus the poor. With the use of rhyme, metaphors and visual imageries, the speaker effectively portrayed how the poorer class youths are negatively stereotyped.